Using people for stop motion (pixilation). I love the effect and really want to experiment with it.
The walk cycle in this is fantastic also the leaping and swimming/diving.. Magnificent!
More cool Pixilation:
Coldplay Strawberry Swing This one's walk cycle is not so realistic, however great use of standing and handstands for different angles. Swimming and being blown away is really effective too!
The PEN Story Pixilation concept with printed photographs. The camera movement even works in this syle. 60.000 pictures and developed 9.600 prints!
Human TetrisThis would be fun to try. I have also seen Space Invaders and other such games done this way.